It is vital to reduce the impact of substance misuse and enhance the behavioral health of all individuals, families, and communities. To do so, EDC uses proven, comprehensive approaches that respond to the complex causes of behavioral health issues including systemic racism, adverse childhood experiences, trauma, and stress.

For decades, we have led initiatives that prepare the behavioral health workforce to provide innovative and effective substance misuse prevention, treatment, and recovery services anchored in culturally responsive and trauma-informed care. Our award-winning consultation services, trainings, and tools are propelling improvements in the quality and equity of programs, practice, and policies across the U.S. and worldwide.

In partnership with practitioners, community leaders, and people with lived experience, we address urgent and emergent behavioral health challenges across the lifespan. Today, these include challenges—such as problem gambling and digital wellness—that can co-occur with substance misuse and mental health issues. All of our work draws on our staff’s expertise in cultural responsiveness, the use of data to drive change, continuous improvement, and prevention and implementation science.

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Here are a few of our resources on substance abuse prevention. To see more, visit our Resources section.

Resource libraries

This resource library contains reports, analyses, surveys, and fact sheets developed as part of EDC’s administration of the MetroWest Adolescent Health Survey from 2006 to 2014.


This resource is designed to help suicide prevention programs in state, tribal, campus, and community settings build and strengthen connections with their substance abuse prevention and treatment counterparts.


This online tool provides guidance for applying the Strategic Prevention Framework process to the prevention of alcohol misuse and abuse.


This tool presents a four-step model that state epidemiological workgroup chairs—or others responsible for creating or rebuilding such groups—can use to strengthen or revitalize their epidemiologic


The Center for Strategic Prevention Support (CSPS) at EDC developed this interactive communications toolkit to help substance abuse prevention practitioners create clear, accurate messages that wou

Resource libraries

This website offers a range of print and online resources developed by EDC to prevent substance misuse and related behavioral health problems.

Resource libraries

This resource library contains programs and strategies for addressing school-based health and safety issues, including bullying, substance abuse, mental health, and school discipline.

Developed for the Massachusetts Health Officers Association, this toolkit prepares local health department staff to respond to the opioid epidemic.

This case study walks through a town's response to developing an early childhood prevention program by walking through how they conducted a needs assessment and developed their capacity building plan.


This report describes three post-overdose interventions that have shown promise in reducing the risk of subsequent overdoses and improving other health outcomes among people who have experienced a non-fatal overdose, highlighting the role of prevention practitioners in supporting these efforts.