It is possible to reduce the impact of opioid and other substance misuse on individuals, families, and communities. To do so, we must understand that substance misuse, early childhood trauma, suicide, and addiction are all interconnected, and that effective programs are multidimensional.

EDC builds the capacity and effectiveness of the nation’s substance misuse prevention workforce through innovative learning opportunities. We help communities weave substance misuse prevention into home visiting programs, after-school settings, and health systems, and we develop trainings that reflect urgent and emergent trends in substance misuse across the lifespan. Our programs are informed by prevention and implementation science, as well as by the multidisciplinary perspectives and cultural competencies of our staff.

Visit Prevention Solutions@EDC or read "Building a Road to Resilience" to learn more about EDC's work to prevent substance misuse.

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Here are a few of our resources on substance abuse prevention. To see more, visit our Resources section.

Developed for the Massachusetts Health Officers Association, this toolkit prepares local health department staff to respond to the opioid epidemic.
Fact sheets
To support Bureau of Substance Addiction Services (BSAS)-funded grantees, BSAS in collaboration with the Center for Strategic Prevention Support (CSPS) convened a 4-part panel discussion on Equity in Everyday Practice between August-November 2021. This document captures the lessons learned from the series.

This case study walks through a town's response to developing an early childhood prevention program by walking through how they conducted a needs assessment and developed their capacity building plan.

Resource libraries

The CSPS resource library provides access to a wealth of information to support substance misuse prevention efforts.


This tool presents a four-step model that state epidemiological workgroup chairs—or others responsible for creating or rebuilding such groups—can use to strengthen or revitalize their epidemiologic


Problem gambling is a public health and social justice issue that impacts individuals, families, and communities.


This worksheet is designed to help you develop a brief inventory of your partners and how you work with them.

Fact sheets

This online fact sheet describes consultation that EDC experts provided to advance Iowa Department of Health and Human Services (Iowa HHS) staff’s efforts to prepare communities to reduce substance


This online toolkit provides specific guidance for applying SAMHSA’s Strategic Prevention Framework to the prevention of opioid misuse and overdoses.